Chidziwitso Choyambira cha Palmitoyl Pentapeptide-4

Dzina La Munda	Zambiri
Dzina la INCI	Palmitoyl Pentapeptide-4
CHO	214047-00-4
Mafananidwe	Palmitoyl pentapeptide-3; Matrixyl; Palmitoyl pentapeptide trifluoroacetic acid; Palmitoyl-Lys-Thr-Thr-Lys-Ser-OH
Ubwino chinsinsi	Woletsa Makwinya / Woletsa Ukalamba

Palmitoyl Pentapeptide-4 Ufa mfundo

Dzina La Munda	Zambiri
fomu	ufa
Maonekedwe	White kapena off-woyera woyera
Purity (HPLC)	≥ 95%, kapena ≥ 98%
Zosunga	Sungani motsekedwa, motetezedwa ku kuwala ndi chinyezi. Sungani kwa nthawi yayitali pa -20°C.
CD	Mabotolo agalasi/pulasitiki, kapena mapaketi okonzedwa kutengera zopempha zapadera.
Manyamulidwe	Kunyamula katundu woyenda mumlengalenga mothamanga komanso motetezeka ku chinyezi.
Pemphani Zitsanzo za Mtengo / Oda

Palmitoyl Pentapeptide-4 Yankho Kufotokozera

Dzina La Munda	Zambiri
fomu	Zamadzi
Maonekedwe	Chotsani Chowonekera Madzi
Zinthu za Peptide	100ppm, 500ppm (Ingasinthidwe mukapempha)
Zosunga	Ikhoza kunyamulidwa kutentha kwa chipinda. Sungani pamalo ouma, amdima pa 2-8°C kuti musunge kwa nthawi yayitali.
CD	1Kg kapena 5kg, kapena ma phukusi osinthidwa malinga ndi zopempha zapadera.
Manyamulidwe	Kunyamula katundu woyenda mumlengalenga mothamanga komanso motetezeka ku chinyezi.
Pemphani Zitsanzo za Mtengo / Oda

Palmitoyl Pentapeptide-4 ndi peptide yokhazikika yomwe imawonjezera kapangidwe ka collagen ndi makulidwe a epidermal kuti isakwiyitse makwinya.

Ubwino ndi Phindu

mbali	tsatanetsatane
Kukondoweza kwa Collagen	Imayendetsa neosynthesis ya macromolecules a extracellular matrix monga collagen, zomwe zimapangitsa kuti pakhale mphamvu yotsutsana ndi makwinya.
Kuthira kwa Anti-GAG & Epidermal	Amaletsa kupanga kwambiri kwa glycosaminoglycans yokhudzana ndi ukalamba wa khungu ndipo amayambitsa kukhuthala kwa epidermal.
Kugwira Ntchito Kosakwiyitsa	Zimathandiza kukonza makwinya a nkhope popanda kufiira kwa khungu kapena kuwonongeka kwa zotchinga zomwe zimayambitsidwa ndi retinol ndi zinthu zina zogwira ntchito.
Kukonza Mapindu Ambiri	Amachepetsa makwinya, mawanga okalamba, mawanga akuda, ndipo amalimbitsa khungu kutengera zomwe munthu wadziyesa yekha.

Ibibazo

Q1: N’chifukwa chiyani Palmitoyl Pentapeptide-4 imatchulidwa kuti ndi “Matrikine”?

A: Matrikines ndi ma peptide opangidwa ndi ma messenger omwe amatha kulamulira ntchito za maselo kudzera mu mgwirizano wapadera wa ma receptor. Pal-KTTKS imatsanzira chidutswa chachilengedwe cha khungu la pro-collagen I. Imagwira ntchito ngati chizindikiro kwa ma fibroblast, zomwe zimawayambitsa kuyambitsa neosynthesis ya macromolecules a extracellular matrix (ECM) monga collagen.

Q2: Kodi cholinga cha mgwirizano wa Palmitic Acid ndi chiyani?

A: Ndondomeko yoyambirira ya pentapeptide (KTTKS) ndi yofanana ndi ionic komanso hydrophilic, zomwe zimapangitsa kuti kulowa m'mapangidwe a khungu la lipid kukhale kovuta. Kuigwirizanitsa ndi unyolo wa aliphatic palmitoyl wa 16-carbon kumawonjezera kwambiri lipophilicity yake komanso kukhazikika kwake, zomwe zimapangitsa kuti ifike bwino mu dermis.

Q3: Kodi njira yake yolimbana ndi ukalamba imasiyana bwanji ndi Retinol?

A: Ngakhale retinol imathandizira kusintha kwa maselo komwe kungayambitse kuyabwa, Pal-KTTKS imagwira ntchito kudzera mu Matrikine signaling kuti iyambe kukonzanso matrix. Zatsimikiziridwa kuti zimathandiza kukonza makwinya popanda kufiira kapena kuwonongeka kwa zotchinga zomwe zimagwirizanitsidwa ndi retinoids, zomwe zimapangitsa kuti ikhale njira yabwino kwambiri pakhungu losavuta kumva.

Q4: Kupatula collagen, ndi zigawo zina ziti zomwe imalamulira?

A: Deta ikusonyeza kuti imayambitsa kukhuthala kwa epidermal ndikuletsa kupanga kwambiri kwa dermal glycosaminoglycans (GAGs) yokhudzana ndi khungu lokalamba, zomwe zimathandiza kuti khungu likhale lolimba komanso lolimba.

Q5: Ndi ubwino wotani wa zachipatala womwe wapezeka poyesa anthu?

Yankho: Mayeso ambiri osatha a anthu amatsimikizira kusintha kwakukulu pakuwoneka kwa makwinya pankhope. Kudziyesa nokha kwa anthu kumasonyezanso kusintha kwakukulu pa kulimba kwa khungu, mawanga a ukalamba, ndi mawanga akuda.