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Copper Tripeptide-1 (CAS: 49557-75-7) Anti-Aging Peptides
PRODUCT PARAMETERS
Copper Tripeptide-1
CAS: 49557-75-7
Anti-aging, Barrier repair
Copper Tripeptide-1 (GHK-Cu) acts as a cellular commander to boost collagen, repair DNA, and neutralize free radicals for firm, ageless skin.
Description
Copper Tripeptide-1 Basic Information
| Field Name | Specification Details |
| INCI Name | Copper Tripeptide-1 |
| CAS No. | 49557-75-7 |
| Synonyms | GHK-Cu; Copper Peptide; (Gly-His-Lys)2Cu.xHAc |
| Key Benefits | Anti-aging, Barrier repair |
Copper Tripeptide-1 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | Blue to Deep Blue powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Copper Tripeptide-1 Solution Specification
| Field Name | Specification Details |
| Form | Liquid |
| Appearance | Blue Transparent Liquid |
| Peptide Content | 1,000ppm – 50,000ppm (Customizable) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Inquiry | [Request a Quote / Order Samples] |
Copper Tripeptide-1 (GHK-Cu) acts as a cellular commander to boost collagen, repair DNA, and neutralize free radicals for firm, ageless skin.

Advantage and Benefit
| Feature | Details |
| Cellular Commander | Modulates gene expression of over 4,000 genes to “reset” skin to a healthier state. |
| ECM Remodeling | Increases collagen, elastin, and glycosaminoglycan synthesis better than Retinol or Vitamin C. |
| DNA & Stem Cell Support | Accelerates wound healing and protects skin stem cells from UV-induced damage. |
| Anti-Inflammatory | Suppresses pro-inflammatory cytokines, making it ideal for post-procedure and sensitive skin. |
| Visible Firming | Clinically proven to reduce wrinkle depth, improve skin density, and enhance elasticity. |
FAQs
Q1: What exactly is Copper Tripeptide-1, and is it the same as GHK-Cu?
A: Yes, Copper Tripeptide-1 is the official INCI name for GHK-Cu. It consists of the tripeptide Glycyl-L-histidyl-L-lysine ($Gly-His-Lys$) complexed with a copper (II) ion. This specific sequence has a high affinity for copper, allowing it to act as a specialized delivery system that transports essential copper ions into the skin cells to activate vital enzymatic processes.
Q2: How does it differ from other “Blue Copper Peptides” like AHK-Cu?
A: While both are blue, their biological targets differ. Copper Tripeptide-1 (GHK-Cu) is the “all-rounder” for skin rejuvenation, targeting collagen synthesis and tissue repair. In contrast, AHK-Cu (Copper Tripeptide-3) is primarily utilized in hair care to stimulate follicle growth. For high-performance anti-aging and dermal remodeling, Copper Tripeptide-1 remains the industry benchmark.
Q3: What makes its “Remodeling” mechanism unique compared to standard collagen boosters?
A: Most peptides simply stimulate the production of new collagen. Copper Tripeptide-1 goes further by regulating Extracellular Matrix (ECM) Remodeling. It balances the activity of Matrix Metalloproteinases (MMPs) and their inhibitors (TIMPs), effectively “cleaning up” damaged, disorganized collagen and replacing it with a neat, youthful fiber network.
Q4: Why is it considered the ultimate “Post-Procedure” recovery ingredient?
A: It is a potent anti-inflammatory agent. GHK-Cu significantly reduces pro-inflammatory cytokines such as $TNF-\alpha$ and $IL-1$, while simultaneously accelerating the synthesis of glycosaminoglycans (like hyaluronic acid). This dual action dramatically shortens downtime after laser treatments or chemical peels by calming “inflammaging” and rebuilding the barrier.
Q5: Are there specific formulation constraints when using Copper Tripeptide-1?
A: Yes. Because it is a metal-complexed peptide, it is sensitive to pH and chelating agents. It performs best at a pH of 5.0 to 7.0. It should not be formulated with strong acids (like high-concentration AHA/BHA) or pure Vitamin C (L-Ascorbic Acid), as these can break the copper-peptide bond, causing the solution to lose its signature blue color and biological activity.
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