Copper Tripeptide-1 (CAS: 49557-75-7) Anti-Aging Peptides

PRODUCT PARAMETERS

Copper Tripeptide-1

CAS: 49557-75-7

Anti-aging, Barrier repair

Copper Tripeptide-1 (GHK-Cu) acts as a cellular commander to boost collagen, repair DNA, and neutralize free radicals for firm, ageless skin.

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Description

Copper Tripeptide-1 Basic Information

Copper Tripeptide-1 Powder Specification

Copper Tripeptide-1  Solution Specification

The mechanism of action of Copper Tripeptide-1

Advantage and Benefit

FAQs

A: Yes, Copper Tripeptide-1 is the official INCI name for GHK-Cu. It consists of the tripeptide Glycyl-L-histidyl-L-lysine ($Gly-His-Lys$) complexed with a copper (II) ion. This specific sequence has a high affinity for copper, allowing it to act as a specialized delivery system that transports essential copper ions into the skin cells to activate vital enzymatic processes.

A: While both are blue, their biological targets differ. Copper Tripeptide-1 (GHK-Cu) is the “all-rounder” for skin rejuvenation, targeting collagen synthesis and tissue repair. In contrast, AHK-Cu (Copper Tripeptide-3) is primarily utilized in hair care to stimulate follicle growth. For high-performance anti-aging and dermal remodeling, Copper Tripeptide-1 remains the industry benchmark.

A: Most peptides simply stimulate the production of new collagen. Copper Tripeptide-1 goes further by regulating Extracellular Matrix (ECM) Remodeling. It balances the activity of Matrix Metalloproteinases (MMPs) and their inhibitors (TIMPs), effectively “cleaning up” damaged, disorganized collagen and replacing it with a neat, youthful fiber network.

A: It is a potent anti-inflammatory agent. GHK-Cu significantly reduces pro-inflammatory cytokines such as $TNF-\alpha$ and $IL-1$, while simultaneously accelerating the synthesis of glycosaminoglycans (like hyaluronic acid). This dual action dramatically shortens downtime after laser treatments or chemical peels by calming “inflammaging” and rebuilding the barrier.

A: Yes. Because it is a metal-complexed peptide, it is sensitive to pH and chelating agents. It performs best at a pH of 5.0 to 7.0. It should not be formulated with strong acids (like high-concentration AHA/BHA) or pure Vitamin C (L-Ascorbic Acid), as these can break the copper-peptide bond, causing the solution to lose its signature blue color and biological activity.

GENOPEP GROUP | The Engine of Your Peptide Innovation

GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.

We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:

  • Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
  • End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
  • Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.

We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.

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