S-Mu-Conotoxin Cniiic Basic Information

Field Name	Basic information
INCI Name	S-Mu-Conotoxin Cniiic
CAS No.	936616-33-0
Synonyms	mu-conotoxin;XEP-018;CONOTOXIN; 5-oxo-L-prolylglycyl-L-cysteinyl-L-cysteinyl-L-asparaginylglycyl-L-prolyl-L-lysylglycyl-L-cysteinyl-L-seryl-L-seryl-L-lysyl-L-tryptophyl-L-cysteinyl-L-arginyl-L-α-aspartyl-L-histidyl-L-alanyl-L-arginyl-L-cysteinyl-, cyclic (3→15),(4→21),(10→22)-tris(disulfide);Conotoxin/Conopeptide/CTX;mu-conotoxin
Key Benefits	Anti-wrinkle

S-Mu-Conotoxin Cniiic Powder Specification

Field Name	Basic information
Form	Powder
Appearance	White to off-white powder
Purity (HPLC)	≥ 95%, or ≥ 98%
Storage Conditions	Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended.
Packaging	Glass/plastic sample bottles, or customized packages based on special requests.
Shipping	Express air freight with moisture-proof protection.
Inquiry	[Request a Quote / Order Samples]

S-Mu-Conotoxin Cniiic Solution Specification

Field Name	Basic information
Form	Liquid
Appearance	Clear Transparent Liquid
Peptide Content	1000 ppm, 500 ppm (Customizable upon request)
Storage Conditions	Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage.
Packaging	1Kg or 5kg, or customized packages based on special requests.
Shipping	Express air freight with moisture-proof protection.
Sample	Request a Quote / Order Samples

S-Mu-Conotoxin Cniiic: A selective NaV 1.4 channel blocker providing safe, Botox-like muscle relaxation for advanced, non-invasive anti-aging.

Advantage and Benefit

Feature	Details
High Selectivity	Specifically blocks NaV 1.4 sodium channels in muscles without affecting cardiac (NaV 1.5) or neuronal channels, ensuring targeted action.
Excellent Safety Profile	No adverse effects on heart or nerves; safer than non‑selective toxins, suitable for topical cosmetic use.
Long‑Lasting Muscle Relaxation	Provides a sustained Botox‑like effect by physically occluding the channel pore, reducing mimic wrinkles without injections.
Non‑Invasive Anti‑Wrinkle	Delivers significant anti‑aging benefits via simple topical application, avoiding needles and invasive procedures.

FAQs

Q1: How does the molecular weight of CnIIIC affect its skin penetration?

A: While it is a 22-amino-acid peptide, its specific folding and lipophilic modifications (in genopep’s proprietary delivery systems) ensure it reaches the neuromuscular junctions effectively for topical results.

Q2: Is there any risk of systemic absorption?

A: No. Its high selectivity for NaV 1.4 and the localized nature of topical application prevent systemic interaction, as confirmed by safety studies on selective conotoxin derivatives.

Q3: Can this be used as a post-procedure maintenance ingredient?

A: Absolutely. It is an excellent recommendation for extending the intervals between botulinum toxin injections by maintaining muscle relaxation.

Q4: What makes this “Marine Conopeptide” so unique compared to other peptides?

Unlike traditional peptides, s-Mu-Conotoxin CnIIIC is a biomimetic version of a potent toxin used by cone snails to paralyze prey. In skincare, it provides a rapid and long-lasting “Botox-like” effect by relaxing mimic muscles through a highly specialized pathway.

Q5: Is it safe for topical use if it’s derived from a toxin?

Yes, it is extremely safe due to its exquisite selectivity. It only targets NaV 1.4 sodium channels distributed in the muscles and does not interfere with channels in the heart (NaV 1.5) or other vital organs. This ensures localized muscle relaxation without systemic side effects.

Q6: How does it help fight “Mimic Wrinkles”?

Mimic wrinkles are caused by repeated muscle contractions. By blocking the sodium channels responsible for transmitting the electrical signal for contraction, the peptide keeps the muscles in a relaxed state, significantly smoothing the skin’s surface.

Q7: Can it replace invasive injections?

While it delivers a significant anti-aging effect via topical application, it is designed as a non-invasive alternative. It allows users to achieve visible wrinkle reduction without the need for needles or clinical procedures.