Professional Cosmetics Peptide Supplier | GENOPEP

Nonapeptide-1 (CAS: 158563-45-2) Brightening Peptides
PRODUCT PARAMETERS
Nonapeptide-1
CAS: 158563-45-2
Brightening / Anti-pigmentation
Nonapeptide-1 is a stable and safe biomimetic peptide that targets the melanogenesis pathway to effectively reduce hyperpigmentation, sun spots, and freckles, delivering a visibly lighter, more radiant, and balanced complexion within a 28-day treatment cycle.
Description
Nonapeptide-1 Basic Information
| Field Name | Basic information |
| INCI Name | Nonapeptide-1 |
| CAS No. | 158563-45-2 |
| Synonyms | L-Methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide; Melanostatine-5; Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2; Nonapeptide-1; |
| Key Benefits | Brightening / Anti-pigmentation |
Nonapeptide-1 Powder Specification
| Field Name | Specification Details |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Nonapeptide-1 Solution Specification
| Field Name | Specification Details |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000ppm (Customizable) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Nonapeptide-1 is a stable and safe biomimetic peptide that targets the melanogenesis pathway to effectively reduce hyperpigmentation, sun spots, and freckles, delivering a visibly lighter, more radiant, and balanced complexion within a 28-day treatment cycle.

Advantage and Benefit
| Feature | Details |
| Upstream Inhibition | Blocks the “melanin signal” before the pigment production even begins. |
| Targeted Brightening | Significant reduction in hyperpigmentation, age spots, and freckles within a 28-day cycle. |
| High Safety Profile | A non-cytotoxic alternative to harsh whitening agents like hydroquinone, safe for sensitive skin. |
| Stable & Compatible | Easily integrated into whitening serums, daily moisturizers, and sun-care formulations. |
FAQs
Q1. What is Nonapeptide-1 and what is its primary function in skincare applications?
A: Nonapeptide-1 is a specialized skin-lightening peptide. Its primary function is to offer control over skin tone by inhibiting the synthesis of melanin, helping to reduce the formation of unwanted pigmentation.
Q2. What is the biological inspiration behind the development of Nonapeptide-1?
A: This peptide is biologically derived from the melanocyte-stimulating hormone (MSH), mimicking certain natural processes to regulate skin pigmentation.
Q3. What is the specific mechanism of action by which Nonapeptide-1 prevents pigmentation?
A: Nonapeptide-1 works at the cellular level by targeting melanocytes (pigment-producing cells). It specifically prevents the activity of tyrosinase, a key enzyme required for the production of melanin.
Q4. How does Nonapeptide-1 improve the overall appearance of the skin?
A: By inhibiting melanin synthesis, Nonapeptide-1 actively lessens existing hyperpigmentation. This results in an evening out of the overall skin tone for a more uniform appearance.
Q5. Is Nonapeptide-1 effective against specific dark spots?
A: Yes. By reducing the formation of new unwanted pigmentation, Nonapeptide-1 is effective in addressing and controlling specific hyperpigmentation concerns, such as brown spots.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.













