Professional Cosmetics Peptide Supplier | GENOPEP
Acetyl Tetrapeptide-15 (CAS:928007-64-1) Soothing and Anti-Inflammatory Peptides
PRODUCT PARAMETERS
Description
Acetyl Tetrapeptide-15 Basic Information
| Field Name | Basic information |
| INCI Name | Acetyl Tetrapeptide-15 |
| CAS No. | 928007-64-1 |
| Synonyms | Acetyl tetrapeptide 15; Skinasensyl;acetyl tetrapeptide-15, AC-PPLY-OH; |
| Key Benefits | Soothing and Anti-Inflammatory/ Sensitive Skin Care |
Acetyl Tetrapeptide-15 Powder Specification
| Field Name | Specification Details |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% (User instruction) |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles,or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Tetrapeptide-15 Solution Specification
| Field Name | Specification Details |
| Product Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000ppm,500ppm Customizable |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Tetrapeptide-15 mimics natural opioids to lower nerve sensitivity and inflammation, effectively soothing redness and discomfort in skin.
The mechanism of Acetyl Tetrapeptide-15
Advantage and Benefit
| Feature | Details |
| Tolerance Reinforcement | Increases the skin’s natural ability to tolerate environmental factors and aggressive cosmetics by modulating nerve sensitivity. |
| Neurogenic Inflammation Relief | Effectively targets the pathways responsible for redness and irritation (CGRP/Substance P). |
| Anti-Itching & Anti-Aching | Specifically engineered to relieve physical discomfort, including chronic or neuropathic stinging sensations. |
| Clinical Versatility | Ideal for post-procedure recovery, hormone replacement-related sensitivity, and daily care for hyper-reactive skin. |
FAQs
Q1: What is the biological origin of Acetyl Tetrapeptide-15 and how does it relate to natural pain management?
A: Acetyl Tetrapeptide-15 is a synthetic peptide derived from endomorphin-2, a natural human $\mu$-opioid agonist. It functions as an “endorphin-like” molecule that mimics the body’s natural opioid peptides to reduce the stimulation of skin nerve endings, providing a selective anti-nociceptive effect to manage skin discomfort.
Q2: How does this peptide improve the “tolerance threshold” of hyper-reactive skin?
A: This peptide works by increasing the threshold of neuronal excitability. By acting on muopioid receptors in the skin, it makes nerve endings less sensitive to external triggers, thereby improving the skin’s natural ability to tolerate environmental factors, aggressive cosmetics, and clinical skin treatments.
Q3: Which specific neurogenic pathways does it target to reduce redness and irritation?
A: It soothes sensitive skin by attenuating key neurogenic inflammation mediators, specifically targeting the CGRP (Calcitonin Gene-Related Peptide) and Substance P pathways. Reducing these mediators directly leads to a decrease in irritation, redness, and the overall inflammatory response.
Q4: Can Acetyl Tetrapeptide-15 alleviate physical sensations like itching or aching?
A: Yes. It is engineered as a potent anti-allergic peptide with specific anti-itching and anti-aching properties. It is particularly effective at preventing and relieving irritant symptoms, including chronic or neuropathic sensations and discomfort caused by hormone replacement or chemical sensitivity.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.
