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Acetyl Tetrapeptide-2 (CAS: 757942-88-4) Anti-Aging Peptides
PRODUCT PARAMETERS
Acetyl Tetrapeptide-2
CAS: 757942-88-4
Anti-Aging, Bust enhancement
Acetyl Tetrapeptide-2 combat skin sagging and dermal disorganization by upregulating structural proteins and organizing elastin fibers to maintain defined facial contours against the effects of gravity.
Description
Acetyl Tetrapeptide-2 Basic Information
| Field Name | Basic information |
| INCI Name | Acetyl Tetrapeptide-2 |
| CAS No. | 757942-88-4 |
| Synonyms | N-Acetyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine; Ac-Lys-Asp-Val-Tyr; Ac-KDVY-OH; |
| Key Benefits | Anti-Aging, Bust enhancement |
Acetyl Tetrapeptide-2 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Tetrapeptide-2 Solution Specification
| Field Name | Basic information |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000 ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | [Request a Quote / Order Samples] |
Acetyl Tetrapeptide-2 combat skin sagging and dermal disorganization by upregulating structural proteins and organizing elastin fibers to maintain defined facial contours against the effects of gravity.

Advantage and Benefit
| Feature | Details |
| Youth Hormone Mimicry | Re-energizes mature skin cells to operate with the metabolic activity and regenerative capacity of younger skin. |
| “Anti-Gravity” Lifting | Specifically targets the organization of elastin fibers through LOXL1/FBLN5 activation to combat facial sagging. |
| Immune Vigilance | Stimulates the maturation of Langerhans cells, boosting the skin’s defense against environmental stressors. |
| Body Contouring | Highly effective for restructuring areas prone to severe sagging, such as the neck, chest, and arms after weight loss. |
FAQs
Q1: How does Acetyl Tetrapeptide-2 “mimic” a youth hormone?
A: It repeats a critical portion of the Thymopentin sequence found in thymopoietin. This mimicry allows the peptide to “re-energize” mature skin cells, signaling them to operate with the metabolic activity and regenerative capacity typically seen in much younger skin.
Q2: What is the relationship between “Peptigravity” and elastin organization?
A: Beyond just stimulating elastin production, this peptide activates two essential glycoproteins: Fibulin 5 (FBLN5) and Lysyl Oxidase-Like 1 (LOXL1). These are fundamental for the correct assembly and functional organization of elastin fibers, ensuring they provide actual resistance and firmness rather than just volume.
Q3: How does it improve the skin’s immune system?
A: By acting on keratinocytes, it induces the synthesis of mediators like GM-CSF. This stimulates the maturation of Langerhans cells and boosts the skin’s own immune vigilance, providing a more robust barrier against external environmental stressors.
Q4: Can this peptide be used for body care after weight loss?
A: Yes. Its ability to increase cell stiffness and improve cohesion between cells and the extracellular matrix (ECM) makes it highly effective for restructuring skin in areas prone to severe sagging, such as the neck, chest, and arms.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.













