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Palmitoyl Tripeptide-5(CAS:623172-56-5)Anti-Wrinkle Peptide
PRODUCT PARAMETERS
Palmitoyl Tripeptide-5
CAS: 623172-56-5
Anti-Wrinkle / Anti-Aging
Palmitoyl Tripeptide-5: TSP-1 biomimicry unlocks & activates TGF-β, boosting collagen/HA synthesis while inhibiting MMPs for firm, resilient skin.
Description
Palmitoyl Tripeptide-5 Basic Information
| Field Name | Basic information |
| INCI Name | Palmitoyl Tripeptide-5 |
| CAS No. | 623172-56-5 |
| Synonyms | Palmitoyl-Lys-Val-Lys-OH; SYN-COLL; Syn-Coll; Cosroma® PT5-1000P; |
| Key Benefits | Anti-Wrinkle / Anti-Aging |
Palmitoyl Tripeptide-5 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Palmitoyl Tripeptide-5 Solution Specification
| Field Name | Basic information |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000 ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | Request a Quote / Order Samples |
Palmitoyl Tripeptide-5: TSP-1 biomimicry unlocks & activates TGF-β, boosting collagen/HA synthesis while inhibiting MMPs for firm, resilient skin.

Advantage and Benefit
| Feature | Details |
| TSP-1 Biomimicry | Mimics thrombospondin‑1 to bind latent TGF‑β complex, unlocking the body‘s own collagen‑building machinery. |
| TGF‑β Activation | Releases and activates TGF‑β, triggering fibroblast receptors to drive synthesis of structural proteins. |
| Collagen & HA Boost | Stimulates neosynthesis of collagen I/III and hyaluronic acid, increasing skin volume, density, and hydration. |
| MMP Inhibition | Suppresses matrix metalloproteinase activity, protecting collagen fibers from degradation for lasting firmness. |
FAQs
Q1:Which types of collagen does it target?
A:It provides comprehensive structural support. Clinical evidence shows that it significantly boosts both Type I and Type III collagen, as well as Fibronectin and Elastin. This restores the skin’s 3D architecture, filling in fine lines and deep-set wrinkles.
Q2:How does Palmitoyl Tripeptide-5 “wake up” the skin’s growth factors?
A: It functions as a bio-mimetic of Thrombospondin-1 (TSP-1). In the skin, TGF-βis often stored in an inactive form. Palmitoyl Tripeptide-5 acts like a “biological key” that binds to and activates this latent TGF-β, which then directly signals fibroblasts to produce massive amounts of new collagen.
Q3: How long does it take to see visible results?
A: While individual results vary, clinical trials using a 2.5% concentration show a visible reduction in wrinkle depth and an improvement in skin texture in as little as 4 to 8 weeks of consistent daily use.
Q4: Is it safe for the delicate eye area?
A: Absolutely. Due to its extreme mildness and zero-irritation profile, Palmitoyl Tripeptide-5 is a star ingredient in premium eye creams. It targets “crow’s feet” and loss of firmness around the lids without the risk of stinging or redness associated with retinoids.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.













