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Tetrapeptide-7 (CAS: 77727-17-4) Soothing and Anti-Inflammatory Peptides
PRODUCT PARAMETERS
Tetrapeptide-7
CAS: 77727-17-4
Soothing / Anti-Inflammatory
Tetrapeptide-7 mimics DHEA to suppress IL-6 inflammation and boost phagocytosis, protecting the dermal matrix for firmer, resilient skin.
Description
Tetrapeptide-7 Basic information
| Field Name | Basic information |
| INCI Name | Tetrapeptide-7 |
| CAS No. | 77727-17-4 |
| Synonyms | Glycyl-L-glutaminyl-L-prolyl-L-arginine;DermaPep A410; Gly-Gln-Pro-Arg (G-Q-P-R) |
| Key Benefits | Soothing / Anti-Inflammatory |
Tetrapeptide-7 Powder Specification
| Field Name | Specification Details |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95% or≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles,or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | [Request a Quote / Order Samples] |
Tetrapeptide-7 Solution Specification
| Field Name | Specification Details |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 100 ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | [Request a Quote / Order Samples] |
Tetrapeptide-7 mimics DHEA to suppress IL-6 inflammation and boost phagocytosis, protecting the dermal matrix for firmer, resilient skin.

Advantage and Benefit
| Feature | Details |
| DHEA-Like Signaling | Acts as a surrogate for declining DHEA levels to “reset” mature skin behavior. |
| Inflammaging Control | Suppresses Interleukin-6 (IL-6) to prevent chronic inflammation-induced matrix degradation. |
| Enhanced Phagocytosis | Stimulates cellular “cleaning crews” to clear debris and alien compounds, boosting skin defense. |
| UV Stress Protection | Reduces UV-induced IL-6 secretions, protecting skin from environmental aggressors. |
| Synergistic Efficacy | Pairs perfectly with repair peptides (e.g., Tripeptide-1) for a comprehensive anti-aging strategy. |
FAQs
Q1: Why is Tetrapeptide-7 called a “youth hormone molecule”?
A: This peptide is designed to mimic the activity of DHEA (Dehydroepiandrosterone), a hormone that naturally declines as we age. By mimicking DHEA’s biological signals, it helps “reset” mature skin to a more youthful state, particularly by managing the inflammation that leads to skin aging.
Q2: How does this peptide address “Inflammaging”?
A: As DHEA levels drop, the skin often sees a spike in Interleukin-6 (IL-6), a pro-inflammatory cytokine. Tetrapeptide-7 works by reducing these basal and UV-induced IL-6 secretions in both keratinocytes and fibroblasts, effectively calming the chronic low-grade inflammation that breaks down skin structure over time.
Q3: What does it mean that this peptide “stimulates phagocytosis”?
A: Similar to the human peptide Tuftsin, Tetrapeptide-7 boosts the skin’s natural cleaning crew. It activates macrophages and lymphocytes to clear away cellular debris and “alien compounds,” which improves the skin’s internal defense mechanisms and overall clarity.
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