Professional Cosmetics Peptide Supplier | GENOPEP
Hexapeptide-11（CAS:161258-30-6） Anti-Aging Peptides
PRODUCT PARAMETERS
Description
Hexapeptide-11 Basic Information
| Field Name | Basic information |
| INCI Name | Hexapeptide-11 |
| CAS No. | 161258-30-6 |
| Synonyms | Peptamide 6; SpecPed® H11;L-Proline,L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-;H-Phe-Val-Ala-Pro-Phe-Pro-OH;FVAPFP |
| Key Benefits | Anti Aging |
Hexapeptide-11 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Hexapeptide-11 Solution Specification
| Field Name | Basic information |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000 ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | Request a Quote / Order Samples |
Hexapeptide-11: boosts proteostasis & Nrf2, remodels ECM. Clinically reduces wrinkles 37%, increases collagen 21%. Anti-aging peptide.
Advantage and Benefit
| Feature | Details |
| Proteostasis Modulation | Enhances UPS and ALS to clear damaged proteins, maintaining cellular protein homeostasis and delaying senescence. |
| Antioxidant Defense | Activates Nrf2 and FOXO3A/sestrin pathways, protecting fibroblasts from oxidative stress‑induced premature aging. |
| ECM Remodeling | Stimulates collagen I/III production and regulates MMPs, improving skin firmness, elasticity, and texture. |
| Clinical Efficacy | Reduces nasolabial fold depth by 37% and increases dermal collagen density by 21% after 8 weeks of use. |
FAQs
Q1: Why is Hexapeptide-11 called a “Proteostasis Modulator”?
A: As skin cells age, they lose the ability to manage and repair proteins, leading to structural collapse. Hexapeptide-11 regulates the Proteostasis Network, helping cells clear out damaged proteins and synthesize high-quality collagen and elastin. It essentially “reboots” the cell’s internal maintenance system.
Q2: How does it interact with the “Longevity Gene” FOXO3A?
A: Hexapeptide-11 activates FOXO3A, a master regulator of cellular longevity. This activation triggers a cascade of stress-response genes (like Sestrins) that shield the cell from oxidative damage and prevent premature senescence. By keeping the “biological clock” of the cell ticking slowly, it significantly delays visible aging.
Q3: Can Hexapeptide-11 help with skin texture and acne scars?
A: Yes. By modulating MMP-2 and MMP-9, it facilitates healthy tissue remodeling. It helps the skin “organize” new collagen fibers more effectively, which is crucial for smoothing out the uneven texture of acne scars and improving the overall refined look of the skin.
Q4: Is it effective for firming the jawline and improving elasticity?
A: Absolutely. It upregulates genes responsible for the synthesis of Collagen and Hyaluronic Acid. By strengthening the dermal extracellular matrix, it provides a measurable “tightening” effect, improving skin tonicity and reducing the sagginess associated with aged fibroblasts.
Q5: How does it protect against “Photo-Aging” at a genetic level?
A: Hexapeptide-11 downregulates aging markers like p53 and ATM, which are triggered by UV-induced DNA damage. By suppressing these “aging signals,” it prevents fibroblasts from entering a permanent state of growth arrest, ensuring the skin maintains its regenerative capacity even under environmental stress.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.
