Professional Cosmetics Peptide Supplier | GENOPEP

Hexapeptide-9(CAS: 1228371-11-6) Anti-Wrinkle Peptide
PRODUCT PARAMETERS
Hexapeptide-9
CAS: 1228371-11-6
Anti-Wrinkle/Anti-Acne/Anti Aging
Hexapeptide-9: matrikine peptide boosts collagen up 117%, HA up 267%. Repairs acne scars, reduces wrinkles 68%. Anti-aging.
Description
Hexapeptide-9 Basic Information
| Field Name | Basic information |
| INCI Name | Hexapeptide-9 |
| CAS No. | 1228371-11-6 |
| Synonyms | Collaxyl; Glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-L-glutamine L-Glutamine,;Collaxyl III; Gly-Pro-Gln-Gly-Pro-Gln |
| Key Benefits | Anti-Wrinkle/Anti-Acne/Anti Aging |
Hexapeptide-9 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Hexapeptide-9 Solution Specification
| Field Name | Basic information |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000 ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | Request a Quote / Order Samples |
Hexapeptide-9: matrikine peptide boosts collagen up 117%, HA up 267%. Repairs acne scars, reduces wrinkles 68%. Anti-aging.

Advantage and Benefit
| Feature | Details |
| Collagen Boost | Stimulates fibroblasts to increase overall collagen production by up to 117%, with collagen IV up by 357%, improving firmness and elasticity. |
| Hyaluronic Acid Enhancement | Enhances HA synthesis by up to 267%, boosting hydration, plumpness, and surface smoothness. |
| Acne Scar Repair | Promotes epidermal regeneration and reorganization, accelerating replacement of damaged tissue with healthy skin to visibly repair acne marks. |
| Wrinkle Reduction | Reduces deep wrinkle surface area by a mean of 68% and moderate wrinkles by 51%, effective against forehead lines and crow‘s feet. |
FAQs
Q1: What makes Hexapeptide-9 a unique “Matrikine” peptide?
A: Hexapeptide-9 is a synthetic matrikine that mimics a naturally occurring fragment of Collagen IV. In the skin, matrikines act as messengers that signal the body to repair itself. By applying Hexapeptide-9, you “trick” the skin into thinking its collagen has broken down, triggering an intense, natural regeneration of the dermal matrix.
Q2: Why is the focus on “Collagen IV” and “DEJ” so important for anti-aging?
A: Most peptides only target Collagen I (volume). Hexapeptide-9 specifically boosts Collagen IV (up to 357%) and XVII, which are the main components of the Dermo-Epidermal Junction (DEJ). A strong DEJ acts like a sturdy foundation for a house; it keeps the skin layers tightly connected, preventing the “flattening” that causes deep sagging and structural wrinkles.
Q3: Can Hexapeptide-9 help with acne scars and skin texture?
A: Yes. Beyond its anti-wrinkle effects, it promotes epidermal differentiation and maturation. This means it helps the skin create healthy, new surface cells more quickly. This accelerated renewal process is highly effective for smoothing out skin texture, healing micro-tears, and reducing the appearance of acne scarring.
Q4: How does it impact Hyaluronic Acid (HA) levels in the skin?
A: Clinical data shows that Hexapeptide-9 can enhance the synthesis of Hyaluronic Acid by up to 267%. This significantly boosts the skin’s internal water-holding capacity, leading to a visible “plumping” effect and a reduction in fine lines caused by dehydration.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.













