Professional Cosmetics Peptide Supplier | GENOPEP
Acetyl Octapeptide-3（CAS: 868844-74-0） Anti-Wrinkle -Peptides
PRODUCT PARAMETERS
Description
Acetyl Octapeptide-3 Basic Information
| Field Name | Basic information |
| INCI Name | Acetyl Octapeptide-3 |
| CAS No. | 868844-74-0 |
| Synonyms | N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-alpha-asparagine; SNAP-8 |
| Key Benefits | Anti-wrinkle, Eye Anti-wrinkle |
Acetyl Octapeptide-3 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Octapeptide-3 Solution Specification
| Field Name | Specification Details |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Octapeptide-3 is a “Botox-like” peptide reducing wrinkles by 63% in 30 days. It offers a non-toxic, non-invasive, and needle-free alternative, providing a natural-looking reduction in wrinkles without the risk of side effects or the “frozen face” look associated with injections.
Advantage and Benefit
| Feature | Details |
| SNARE Complex Inhibition | Mimics SNAP-25 and competitively occupies its position in the SNARE complex, destabilizing complex formation and inhibiting neurotransmitter release. |
| Reversible Muscle Relaxation | Unlike Botox® which causes paralysis, Acetyl Octapeptide-3 reversibly relaxes facial muscles, avoiding the “frozen face” look while smoothing expression lines. |
| Deep Wrinkle Reduction | Clinical studies show up to 63% reduction in wrinkle depth after 30 days of twice-daily use, outperforming many conventional peptides. |
| Non-Toxic & Needle-Free | Provides a safe, non-invasive alternative to botulinum toxin injections with no risk of side effects, suitable for at-home topical applications. |
| Multi-Format Versatility | Exceptionally effective in targeted eye serums (crow’s feet), forehead and smile line treatments, high-end anti-aging creams, and daily maintenance products. |
FAQs
Q1: How does Acetyl Octapeptide-3 achieve its “Botox-like” effect?
A: Acetyl Octapeptide-3 is a potent modulator of the SNARE complex. It mimics the protein SNAP-25 and competitively occupies its position within the complex. This interference destabilizes the SNARE formation, significantly inhibiting the release of neurotransmitters (catecholamines) that trigger facial muscle contractions. By reversibly relaxing these muscles, it prevents the formation of expression lines and deep wrinkles.
Q2: What is the primary clinical advantage of Acetyl Octapeptide-3 over Acetyl Hexapeptide-8 (Argireline)?
A: While both peptides target the same mechanism, Acetyl Octapeptide-3 is an evolution of the hexapeptide structure. As an octapeptide (8 amino acids), it exhibits higher potency and deeper skin penetration. Clinical studies demonstrate that it can reduce wrinkle depth by up to 63% within 30 days, making it a more powerful choice for “high-intensity” anti-aging and expression-line treatments.
Q3: How does this peptide compare to Botulinum Toxin (Botox®) injections?
A: Acetyl Octapeptide-3 offers a non-toxic, non-invasive, and needle-free alternative. Unlike Botox®, which permanently cleaves the SNARE complex and can lead to muscle paralysis, our octapeptide works through competitive inhibition. This means the muscle relaxation is reversible and safer, providing a natural-looking reduction in wrinkles without the risk of side effects or the “frozen face” look associated with injections.
Q4: What are the best application formats for this ingredient?
A: Due to its specific mechanism targeting expression muscles, it is exceptionally effective in:
- Targeted Eye Serums: To treat crow’s feet.
- Forehead & Smile Line Treatments: For localized expression line reduction.
- High-End Anti-Aging Creams: As a core active for “lifting” and “smoothing” claims.
- Daily Maintenance: To prolong the effects of professional aesthetic procedures.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.
