Professional Cosmetics Peptide Supplier | GENOPEP
Acetyl Tetrapeptide-5 (CAS: 820959-17-9） Dark Circles Reduction Peptides
PRODUCT PARAMETERS
Description
Acetyl Tetrapeptide-5 Basic Information
| Field Name | Basic information |
| INCI Name | Acetyl Tetrapeptide-5 |
| CAS No. | 820959-17-9 |
| Synonyms | Eyeseryl; Depuffin; N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine; Acetyl tetrapeptide-5 |
| Key Benefits | Dark Circles reduction/Reducing Eye Bags |
Acetyl Tetrapeptide-5 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Tetrapeptide-5 Solution Specification
| Field Name | Specification Details |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 500ppm – 1000ppm (Customizable) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Tetrapeptide-5: ACE inhibitor boosts lymph circulation, reduces dark circles & puffiness. Clinical: 14‑day improvement. Non‑irritating eye contour.
Advantage and Benefit
| Feature | Details |
| Anti-Edema Action | Reduces fluid accumulation by inhibiting ACE activity and lowering vascular permeability. |
| Lymphatic Drainage | Promotes the microcirculation in the periocular area to “de-puff” tired-looking eyes. |
| Glycation Inhibition | Prevents protein cross-linking in the eye area, maintaining tissue elasticity to prevent permanent bags. |
| Dark Circle Relief | Improves blood flow and reduces stasis to lighten the appearance of vascular dark circles. |
| Rapid Results | Clinically proven to show visible reduction in eye puffiness in as little as 15 days. |
FAQs
Q1:What is the mechanism by which Acetyl Tetrapeptide‑5 reduces vascular dark circles？
A:Acetyl Tetrapeptide‑5 (Eyeseryl®) reduces vascular dark circles by inhibiting ACE‑1 activity, which lowers vascular permeability and prevents fluid leakage, while promoting lymphatic drainage to clear stagnant blood responsible for the bluish‑purple tone. It also inhibits glycation to preserve periorbital collagen elasticity. Clinical data show visible dark circle reduction within 14 days.
Q2: How does Acetyl Tetrapeptide-5 specifically address morning facial puffiness?
A: Morning facial puffiness is often a result of fluid stasis during sleep. Acetyl Tetrapeptide-5 targets this by inhibiting the Angiotensin-Converting Enzyme (ACE), which triggers a cascade that improves lymphatic drainage and microcirculation. By actively “flushing out” excess fluid retained in the interstitial compartments, it helps restore a more defined facial contour shortly after application.
Q3: What is the relationship between “Capillary Permeability” and a swollen face?
A: When capillary walls become too permeable, fluid “leaks” into the surrounding skin tissue, leading to a swollen, heavy appearance. This peptide acts as a vascular stabilizer, decreasing permeability and strengthening the skin’s barrier. This prevents the initial leakage, ensuring that the face remains sculpted rather than retaining unwanted water weight.
Q4: Can Acetyl Tetrapeptide-5 improve the overall “firmness” of the face while reducing edema?
A: Yes, it offers a dual-benefit approach. While its anti-edema properties handle fluid-related swelling, its anti-glycation effect protects the skin’s structural proteins. By preventing sugar molecules from damaging collagen fibers, it preserves the skin’s elasticity and strength, ensuring that once the puffiness is gone, the skin remains firm and lifted.
Q5: How does its “Hydroscopic” nature contribute to skin health?
A: Beyond its circulation benefits, Acetyl Tetrapeptide-5 is a powerful humectant. It draws moisture into the skin to provide deep hydration without contributing to edema. This “hydroscopic” action ensures the skin remains smooth and plump from a healthy moisture balance, rather than appearing “puffy” from fluid retention.
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