Professional Cosmetics Peptide Supplier | GENOPEP
Acetyl Hexapeptide-8（CAS: 616204-22-9)- Anti-Wrinkle -Peptides
PRODUCT PARAMETERS
Description
Acetyl Hexapeptide-8 Basic Information
| Field Name | Basic information |
| INCI Name | Acetyl Hexapeptide-8 |
| CAS No. | 616204-22-9 |
| Synonyms | Argireline;Ac-Glu-Glu-Met-Glu-Arg-Arg-NH2;N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide;Acetyl Hexapeptide-3/Acetyl Hexapeptide-8; |
| Key Benefits | Anti-wrinkle |
Acetyl Hexapeptide-8 Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Hexapeptide-8 Solution Specification
| Field Name | Basic information |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Peptide Content | 1000 ppm, 500 ppm (Customizable upon request) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Sample | Request a Quote / Order Samples |
Acetyl Hexapeptide-8: A non-toxic Botox alternative. Inhibits SNARE complex to relax muscles and reduces wrinkle depth by 32% in 28 days.
Advantage and Benefit
| Feature | Details |
| SNARE Complex Inhibition | Mimics SNAP-25 to competitively block SNARE complex formation, reducing acetylcholine release and relaxing facial muscles. |
| Clinically Proven Anti‑Wrinkle | Reduces periorbital wrinkles by 32% (5%, 28 days) to 48.9% (60 Chinese women, RCT) without toxicity. |
| Extremely High Safety Margin | 4,000 times less toxic than botulin toxin; non‑irritating and well‑tolerated for topical use. |
FAQs
Q1: Why is Acetyl Hexapeptide-8 called “Botox in a Jar”?
A: It mimics the effect of Botox by modulating the same biological pathway. It prevents muscles from contracting too intensely by interfering with the signal sent from nerves to facial muscles. This leads to a visible softening of expression lines without the need for needles or the risk of facial paralysis.
Q2: How does it specifically target expression lines?
A: Every time you smile or frown, your nerves release neurotransmitters to contract your muscles. Acetyl Hexapeptide-8 works by destabilizing the protein complex required for this release. By dampening the signal, the muscles remain more relaxed, allowing the skin above to stay smooth and uncreased.
Q3: Is it safe for long-term daily use?
A: Unlike injectable neurotoxins which require medical supervision, Acetyl Hexapeptide-8 is a gentle, topical peptide. It does not cause systemic side effects or skin irritation. It is ideal for daily preventative aging routines, especially for users who want to delay the need for clinical procedures.
Q4: Can I use it alongside Retinol or Vitamin C?
A: Yes. Acetyl Hexapeptide-8 is highly stable and complements other anti-aging actives. While Retinol works on cell turnover and Vitamin C on brightening, this peptide addresses the mechanical cause of wrinkles (muscle movement), providing a multi-dimensional approach to rejuvenation.
Q5: How soon can I expect to see the “smoothing” effect?
A: While some users notice a subtle “soft-focus” effect shortly after application due to hydration, the biological muscle-relaxing effect typically builds over 15 to 30 days of consistent, twice-daily use.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.
