Professional Cosmetics Peptide Supplier | GENOPEP
Acetyl Hydroxyproline (CAS: 39966-33-7) Anti-Aging Peptides
PRODUCT PARAMETERS
Description
Acetyl Hydroxyproline Basic Information
| Field Name | Basic information |
| INCI Name | Acetyl Hydroxyproline |
| CAS No. | 39966-33-7 |
| Synonyms | N-Acetyl-L-Hydroxyproline; (2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid; Acetyl Hydroxyproline USP/EP/BP |
| Key Benefits | Anti-aging, Anti-pigmentation, Brightening |
Acetyl Hydroxyproline Powder Specification
| Field Name | Basic information |
| Form | Powder |
| Appearance | White to off-white powder |
| Purity (HPLC) | ≥ 95%, or ≥ 98% |
| Storage Conditions | Store sealed, protected from light and moisture. Long-term storage at -20°C is recommended. |
| Packaging | Glass/plastic sample bottles, or customized packages based on special requests. |
| Shipping | Express air freight with moisture-proof protection. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Hydroxyproline Solution Specification
| Field Name | Specification Details |
| Form | Liquid |
| Appearance | Clear Transparent Liquid |
| Concentration | 1000ppm – 5000ppm (Customizable) |
| Storage Conditions | Can transport at room temperature. Store in a dry, dark place at 2-8°C for long term storage. |
| Packaging | 1Kg or 5kg, or customized packages based on special requests. |
| Inquiry | [Request a Quote / Order Samples] |
Acetyl Hydroxyproline inhibits AGE formation and protein crosslinking to prevent skin yellowing and stiffness for a youthful look.
Advantage and Benefit
| Feature | Details |
| Advanced Anti-Glycation | Effectively inhibits the formation of AGEs, preventing the “browning” of skin proteins. |
| Collagen Architecture | Acts as a direct precursor and stabilizer for the collagen triple helix structure. |
| Skin Firming | Prevents protein cross-linking that leads to fiber stiffness and loss of elasticity. |
| Bioavailability | The acetylated form offers superior skin penetration compared to free L-hydroxyproline. |
| Brightening Effect | Addresses “Sallowness” by managing the metabolic by-products of oxidative stress. |
FAQs
Q1: What is the primary function of Acetyl-Hydroxyproline in anti-aging skincare?
A: Acetyl-Hydroxyproline is a high-performance amino acid derivative specifically designed to combat Glycation, a major cause of skin aging. It acts as a potent inhibitor of Advanced Glycation End-products (AGEs). By preventing the non-enzymatic reaction between sugars and skin proteins (like collagen), Acetyl- Hydroxyproline stops the formation of cross-links that lead to dermal stiffening, loss of elasticity, and the characteristic “yellowing” or dullness of aging skin.
Q2: How does Acetyl-Hydroxyproline protect the structural integrity of the dermis?
A: Beyond merely inhibiting sugar-protein bonding, Acetyl-Hydroxyproline plays a vital role in maintaining cellular contractile forces. In glycated skin, fibroblasts lose their ability to contract and organize the extracellular matrix. Clinical data demonstrate that Acetyl-Hydroxyproline prevents this cellular dysfunction, ensuring that fibroblasts remain active and capable of maintaining a firm, resilient, and structurally sound dermal framework.
Q3: Can Acetyl-Hydroxyproline help with “Skin Yellowing” (Sallowness)?
A: Yes. The accumulation of AGEs often results in a brownish or yellowish tint to the skin, known as the “Maillard reaction.” Acetyl-hydroxyproline significantly reduces the formation of Carboxymethyl Lysine (CML) and other pigmented glycation markers. Regular use helps restore a healthy, translucent complexion by preventing the oxidative and glycative stress that leads to sallow, tired-looking skin.
Q4: What are the formulation guidelines for incorporating Acetyl- Hydroxyproline?
A: Acetyl-Hydroxyproline is highly stable and versatile for modern formulations.
- Solubility: Highly water-soluble.
- Stability: Stable within a pH range of 3.5 to 7.0.
- Compatibility: It pairs exceptionally well with antioxidant peptides and brightening agents (like Vitamin C or Niacinamide) to create a multi-dimensional defense against environmental and metabolic aging.
GENOPEP GROUP | The Engine of Your Peptide Innovation
GENOPEP Group is a leading global peptide technology solutions provider, specializing in R&D, manufacturing, and commercialization in the fields of skin science and biopharmaceuticals. Supported by advanced scientific capabilities and a fully integrated supply chain, we deliver efficient and reliable innovation support to skincare brands worldwide.
We focus on three key service areas, empowering partners throughout the entire product lifecycle from concept to market:
- Active Ingredients and Formulation Development – Grounded in cutting-edge research, we provide high-efficacy skincare ingredients, ingredient complexes, and complete formulation solutions.
- End-to-End Production Support – Covering the full journey from lab-scale R&D and pilot optimization to commercial manufacturing, ensuring consistent product quality and reliable supply.
- Custom Synthesis Services – With strong capabilities in novel molecule development, we specialize in the design, synthesis, and preparation of peptide-based novel ingredients and related reference standards.
We believe in technology-driven products and collaboration-driven value. GENOPEP is not just a supplier—we are your trusted innovation partner, dedicated to co-creating the next generation of skincare solutions with you.
